Document Type: Short Communication
Department of Pathology, Bushehr University of Medical Sciences, Bushehr, Iran
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Iranian Veterinary Organization, Tehran, Iran
Department of Poultry Diseases, RAZI Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
Peste des Petits Ruminants (PPR) is caused by a morbillivirus from the Paramyxoviridae family and infected animals especially goats show clinical signs such as necrotic stomatitis, enteritis, and pneumonia. The disease is endemic in Iran. PPR virus has 4 lineages which are closely related to the geographical regions. Information about the lineage of the virus is helpful for monitoring the disease in different regions of a country. Phylogenetic studies lead to having strategies against new lineages which may enter from other countries. The current research studies PPR virus detected by PCR phylogenetically in a small ruminant flock with PPR clinical signs. The goats in a flock in Alborz province showed clinical signs of PPR and 10% of them died. Oral swabs and blood samples were taken from 2 affected goats. RT-PCR was conducted for the detection of RNA of the virus, and then the sequence of the obtained RNA was analyzed phylogenetically. All the samples were positive for the presence of PPR virus and all of them belonged to the lineage IV. The isolates had high homology with each other and even with the isolates from different countries. Control of animals moving through the borders of Iran and increasing vaccination coverage in the country is essential for preventing the entrance of new isolates and incidence of outbreaks in Iran. According to the eradication program of Oie, Iran is attempting to control and eradicate the disease until 2030, in this way increasing vaccination is one of our strategies which its coverage should be improved throughout the country.