Document Type : Original Articles
Authors
1
Thalassemia &Hemoglobinopathy Research center, Health research institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2
Department of Biology, Izeh Branch, Islamic Azad University, Izeh, Iran
3
izmir ekonomi university, Faculti of medical science,izmir, Turkey.
4
Department of Biology, Izeh Branch, Islamic Azad University
5
Faculty member of Thalassemia &Hemoglobinopathy Research center, research institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
10.22092/ari.2024.365910.3163
Abstract
This study looks at how common cancer is, how inflammatory factors compare, and how inflammatory markers (acute phase protein C, erythrocyte sedimentation rate, and plasma viscosity) can be used to diagnose cancer in primary care.
We included newly diagnosed patients of all types of malignancy (children and adults) in this retrospective study from 2018 to 2023. The results of CRP, ESR, Plasma Viscosity tests, and demographic data (age, gender, type of malignancy, and survival) were completed. Research data were analyzed using t-test and Chi-Square statistical methods. According to the results, the average ESR and plasma viscosity were higher in patients who died than in patients who survived (p<0.05). In addition, it was shown that there was a significant relationship between the age and gender of the patients and their survival (p<0.05). It was also shown that there was a significant relationship between the survival of patients with ESR, CRP, and plasma viscosity in different cancers (p<0.05). On the other hand, it was shown that there was a significant correlation between ESR, CRP, and plasma viscosity between different cancers (p<0.05).
Based on the results, it was shown that the average ESR and plasma viscosity were higher in patients who died than in patients who survived (p<0.05). In addition, it was shown that there was a significant relationship between the age and gender of the patients with their survival (p<0.05). It was also shown that there was a significant relationship between survival of patients with ESR, CRP and plasma viscosity in different cancers (p<0.05). On the other hand, it was shown that there was a significant correlation between ESR, CRP and plasma viscosity between different cancers (p<0.05).
To halt the progression of acute inflammation to chronic inflammation and mitigate its harmful implications, it is essential to reduce the inflammatory response. Efficient management of inflammation is crucial in preventing patient mortality and is thus essential for the treatment and survival of patients with malignancies.
Keywords
Main Subjects
)