Prevalence and risk factors of various gastrointestinal malignancies

Document Type : Original Articles

Authors

1 Department of Physiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Thalassemia &Hemoglobinopathy Research center, Health research institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Thalassemia and Hemoglobinopathy Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

4 Faculty member of Thalassemia &Hemoglobinopathy Research center, research institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

10.22092/ari.2024.366690.3286

Abstract

Gastrointestinal (GI) cancers are among the most common and fatal tumors globally, with significant variation in incidence caused by factors such as inheritance, lifestyle, and diet. Understanding the prevalence and related risk factors is essential for improving preventative and treatment techniques.
Data was collected from patients admitted to Baqaei Hospital from 2019 to 2022. The questionnaire included: demographic data (age and sex), occupation, location of malignancy, genetic history, occupation of the patient, smoking, underlying disease (hypertension, diabetes, rheumatism), performing physical activities (exercise), presence of metastasis to other areas and complete survival became. The data analysis of this study was done by statistical software: SPSS, linear regression and unadjusted logistic regression were calculated and analyzed. T-test and chi-square statistical methods were also used for analysis in this study.
The results of this study showed that the survival rate in patients with gastrointestinal malignancies has a significant relationship with age, family history, tumor location (colon and pancreas), history of smoking, concomitant disease, metastasis (rectal cancer), and physical activity. The average age of death people is 66.05 years. Among them, approximately 20.4% had a type of cancer according to family history. Also, 50% had metastasis, 44.8% had smoking, 74.8% had background disorder, and 99.6% had not exercised. Physical activity was significantly lower in deceased patients, and fewer deaths occurred in people with high physical activity levels. Rectal cancer had the highest percentage of metastasis among living and deceased patients. It will be useful to carry out more studies to determine the clinical and demographic factors that affect the survival of patients with colorectal cancer, so it is necessary to inform the public to consult a doctor as soon as possible and do examinations.

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