Nanonbiosensors; Rapid detection of Salmonella, Clostridium, Escherichia, and Brucella spp. infections

Document Type : Review Article

Authors

1 PhD student of avian disease health at Shahid Chamran University, Ahvaz, Iran

2 Islamic Azad University of Shoushtar, Khuzestan, Iran

3 Department of Science, Urmia University, Urmia, Iran.

4 Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

10.32592/ARI.2025.80.2.385

Abstract

Abstract
Zoonotic diseases, which are infectious diseases transmitted from animals to humans, represent a significant global health concern. Despite efforts to eradicate or control these diseases, healthcare systems continue to face a substantial burden due to their re-emergence. Early and accurate detection of bacterial pathogens is crucial to prevent the potential health consequences associated with zoonotic infections. However, conventional diagnostic methods such as Polymerase Chain Reaction (PCR), culture-based techniques, and immunological assays have limitations, including costliness, labor-intensiveness, and lengthy turnaround times for results. There is an increasing interest in developing faster, more accurate, and cost-effective diagnostic methods to address these challenges. Nanobiosensors are emerging as promising tools for rapidly detecting infectious disease agents. These devices utilize biological recognition elements to detect specific pathogens and have the potential to revolutionize diagnostic practices. Additionally, incorporating nanotechnology, particularly Nano Particles (NPs), has been shown to enhance the performance of biosensors by improving their specificity and sensitivity. This review explores the application of biosensors and nanobiosensors to rapidly detect Salmonella, Clostridium, Escherichia, and Brucella spp. Infections. These innovative technologies offer several advantages over traditional diagnostic methods, including reduced cost, simplified workflows, and faster results. Nanobiosensors can detect the presence of bacterial pathogens in various sample types, including environmental samples, animal specimens, and clinical samples, making them versatile tools for disease surveillance and control. Moreover, nanobiosensors have shown promise in enhancing the sensitivity and specificity of detection assays, enabling the early identification of Salmonella, Clostridium, Escherichia, and Brucella spp, even at low concentrations. By leveraging advancements in nanotechnology, researchers can further improve the performance and reliability of biosensors for zoonotic disease diagnosis. Overall, integrating biosensors and nanotechnology holds great potential for enhancing the detection and characterization of Salmonella, Clostridium, Escherichia, and Brucella spp. These innovative diagnostic tools can revolutionize disease surveillance efforts, mitigate the spread of zoonotic diseases, and ultimately improve public health outcomes on a global scale.

Keywords

Main Subjects

References

  1. Sadr S, Lotfalizadeh N, Ghafouri SA, Delrobaei M, Komeili N, Hajjafari A. Nanotechnology innovations for increasing the productivity of poultry and the prospective of nanobiosensors. Veterinary Medicine and Science. 2023;9(5):2118-31.
  2. Heshmati F, Sangar SG, Amoozadehsamakoosh A, Azadi E, Komeili N. The Role of Metallic Nanoparticles in the Prevention and Treatment of Parasitic Diseases in Poultry. Journal of World’s Poultry Science. 2023;2(3):13-9.
  3. Hosseini AM, Dianaty S, Shahhosseini S, Biglarifard R, Razmi R, Komeili N, et al. Advances in Nanotechnology for Enhanced Leukemia Therapy: A Systematic Review of In Vivo Studies. Journal of Lab Animal Research. 2023;2(6):86-99.
  4. Hajjafari A, Sadr S, Rahdar A, Bayat M, Lotfalizadeh N, Dianaty S, et al. Exploring the integration of nanotechnology in the development and application of biosensors for enhanced detection and monitoring of colorectal cancer. Inorganic Chemistry Communications. 2024:112409.
  5. Sadr S, Lotfalizadeh N, Abbasi AM, Soleymani N, Hajjafari A, Roohbaksh Amooli Moghadam E, et al. Challenges and prospective of enhancing hydatid cyst chemotherapy by nanotechnology and the future of nanobiosensors for diagnosis. Tropical Medicine and Infectious Disease. 2023;8(11):494.
  6. Pandey A, Gurbuz Y, Ozguz V, Niazi JH, Qureshi A. Graphene-interfaced electrical biosensor for label-free and sensitive detection of foodborne pathogenic E. coli O157: H7. Biosensors and Bioelectronics. 2017;91:225-31.
  7. Kaya HO, Cetin AE, Azimzadeh M, Topkaya SN. Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives. Journal of Electroanalytical Chemistry. 2021;882:114989.
  8. Johnson AJ, Martin DA, Karabatsos N, Roehrig JT. Detection of anti-arboviral immunoglobulin G by using a monoclonal antibody-based capture enzyme-linked immunosorbent assay. Journal of clinical microbiology. 2000;38(5):1827-31.
  9. Libera K, Konieczny K, Grabska J, Szopka W, Augustyniak A, Pomorska-Mól M. Selected livestock-associated zoonoses as a growing challenge for public health. Infectious disease reports. 2022;14(1):63-81.
  10. Bigdeli IK, Yeganeh M, Shoushtari MT, Zadeh MK. Electrochemical impedance spectroscopy (EIS) for biosensing. Nanosensors for Smart Manufacturing: Elsevier. 2021;p:533-54.
  11. Deng J, Zhao S, Liu Y, Liu C, Sun J. Nanosensors for diagnosis of infectious diseases. ACS Applied Bio Materials. 2020;4(5):3863-79.
  12. Soni A, Surana RK, Jha SK. Smartphone based optical biosensor for the detection of urea in saliva. Sensors and Actuators B: Chemical. 2018;269:346-53.
  13. Zhang H, Xue L, Huang F, Wang S, Wang L, Liu N, et al. A capillary biosensor for rapid detection of Salmonella using Fe-nanocluster amplification and smart phone imaging. Biosensors and Bioelectronics. 2019;127:142-9.
  14. Zhao W, Xing Y, Lin Y, Gao Y, Wu M, Xu J. Monolayer graphene chemiresistive biosensor for rapid bacteria detection in a microchannel. Sensors and Actuators Reports. 2020;2(1):100004.
  15. Debnath N, Das S. Nanobiosensor: current trends and applications. NanoBioMedicine. 2020:389-409.
  16. Christopher FC, Kumar PS, Christopher FJ, Joshiba GJ, Madhesh P. Recent advancements in rapid analysis of pesticides using nano biosensors: a present and future perspective. Journal of cleaner production. 2020;269:122356.
  17. Sadani K, Nag P, Thian XY, Mukherji S. Enzymatic optical biosensors for healthcare applications. Biosensors and Bioelectronics: X. 2022;12:100278.
  18. Ertürk G, Mattiasson B. Molecular imprinting techniques used for the preparation of biosensors. Sensors. 2017;17(2):288.
  19. Seo SE, Tabei F, Park SJ, Askarian B, Kim KH, Moallem G, et al. Smartphone with optical, physical, and electrochemical nanobiosensors. Journal of Industrial and Engineering Chemistry. 2019;77:1-11.
  20. Zhang Y, Duan B, Bao Q, Yang T, Wei T, Wang J, et al. Aptamer-modified sensitive nanobiosensors for the specific detection of antibiotics. Journal of Materials Chemistry B. 2020;8(37):8607-13.
  21. Zhong W. Nanomaterials in fluorescence-based biosensing. Analytical and Bioanalytical Chemistry. 2009;394:47-59.
  22. Vidal P, Martinez M, Hernandez C, Adhikari AR, Mao Y, Materon L, et al. Development of chromatic biosensor for quick bacterial detection based on polyvinyl butyrate-polydiacetylene nonwoven fiber composites. European Polymer Journal. 2019;121:109284.
  23. Jeong W-j, Choi S-H, Lee H-s, Lim Y-b. A fluorescent supramolecular biosensor for bacterial detection via binding-induced changes in coiled-coil molecular assembly. Sensors and Actuators B: Chemical. 2019;290:93-9.
  24. Ahmadi H, Heidarzadeh H, Taghipour A, Rostami A, Baghban H, Dolatyari M, et al. Evaluation of single virus detection through optical biosensor based on microsphere resonator. Optik. 2014;125(14):3599-602.
  25. Zhao Y, Tong R-j, Xia F, Peng Y. Current status of optical fiber biosensor based on surface plasmon resonance. Biosensors and Bioelectronics. 2019;142:111505.
  26. Arwin H. TIRE and SPR-enhanced SE for adsorption processes. Ellipsometry of Functional Organic Surfaces and Films: Springer; 2014. p. 249-64.
  27. Blair EO, Corrigan DK. A review of microfabricated electrochemical biosensors for DNA detection. Biosensors and Bioelectronics. 2019;134:57-67.
  28. Ferreira D, Seca AM, Diana C, Silva AM. Targeting human pathogenic bacteria by siderophores: a proteomics review. Journal of proteomics. 2016;145:153-66.
  29. Majdinasab M, Mishra RK, Tang X, Marty JL. Detection of antibiotics in food: New achievements in the development of biosensors. TrAC Trends in Analytical Chemistry. 2020;127:115883.
  30. Yi-Xian W, Zun-Zhong Y, Cheng-Yan S, Yi-Bin Y. Application of aptamer based biosensors for detection of pathogenic microorganisms. Chinese Journal of Analytical Chemistry. 2012;40(4):634-42.
  31. Gopal J, Narayana JL, Wu H-F. TiO2 nanoparticle assisted mass spectrometry as biosensor of Staphylococcus aureus, key pathogen in nosocomial infections from air, skin surface and human nasal passage. Biosensors and Bioelectronics. 2011;27(1):201-6.
  32. Suaifan GA, Alhogail S, Zourob M. Rapid and low-cost biosensor for the detection of Staphylococcus aureus. Biosensors and Bioelectronics. 2017;90:230-7.
  33. Ahari H, Hedayati M, Akbari-adergani B, Kakoolaki S, Hosseini H, Anvar A. Staphylococcus aureus exotoxin detection using potentiometric nanobiosensor for microbial electrode approach with the effects of pH and temperature. International journal of food properties. 2017;20(2):1578-87.
  34. Beltrán-Pineda M, Peña-Solórzano D, Sierra CA. Nanobiosensors for pathogenic agents detection. Journal of the Brazilian Chemical Society. 2021;32:1687-710.
  35. Purohit B, Vernekar PR, Shetti NP, Chandra P. Biosensor nanoengineering: Design, operation, and implementation for biomolecular analysis. Sensors International. 2020;1:100040.
  36. Shoukat S, Wani H, Ali U, Para PA, Ara S, Ganguly S. Brucellosis: A current review update on zoonosis. 2017.
  37. Seleem MN, Boyle SM, Sriranganathan N. Brucellosis: a re-emerging zoonosis. Veterinary microbiology. 2010;140(3-4):392-8.
  38. Hajia M, Fallah F, Angoti G, Karimi A, Rahbar M, Gachkar L, et al. Comparison of methods for diagnosing brucellosis. Laboratory Medicine. 2013;44(1):29-33.
  39. Critchley E. A comparison of human and animal botulism: a review. Journal of the Royal Society of Medicine. 1991;84(5):295-8.
  40. Lévêque C, Ferracci G, Maulet Y, Mazuet C, Popoff MR, Blanchard M-P, et al. An optical biosensor assay for rapid dual detection of Botulinum neurotoxins A and E. Scientific Reports. 2015;5(1):17953.
  41. Wictome M, Newton K, Jameson K, Hallis B, Dunnigan P, Mackay E, et al. Development of an in vitro bioassay for Clostridium botulinum type B neurotoxin in foods that is more sensitive than the mouse bioassay. Applied and Environmental Microbiology. 1999;65(9):3787-92.
  42. Wang Y, Schill KM, Fry HC, Duncan TV. A quantum dot nanobiosensor for rapid detection of botulinum neurotoxin serotype E. ACS sensors. 2020;5(7):2118-27.
  43. Vidic J, Manzano M, Chang C-M, Jaffrezic-Renault N. Advanced biosensors for detection of pathogens related to livestock and poultry. Veterinary research. 2017;48:1-22.
  44. Zhu D, Yan Y, Lei P, Shen B, Cheng W, Ju H, et al. A novel electrochemical sensing strategy for rapid and ultrasensitive detection of Salmonella by rolling circle amplification and DNA–AuNPs probe. Analytica Chimica Acta. 2014;846:44-50.
  45. Sun Q, Zhao G, Dou W. An optical and rapid sandwich immunoassay method for detection of Salmonella pullorum and Salmonella gallinarum based on immune blue silica nanoparticles and magnetic nanoparticles. Sensors and Actuators B: Chemical. 2016;226:69-75.
  46. Sonawane SK, Arya SS, Leblanc JGJ, Jha N. Use of nanomaterials in the detection of food contaminants. 2014.
  47. Le TN, Tran TD, Kim MI. A convenient colorimetric bacteria detection method utilizing chitosan-coated magnetic nanoparticles. Nanomaterials. 2020;10(1):92.
  48. Pu H, Xu Y, Sun D-W, Wei Q, Li X. Optical nanosensors for biofilm detection in the food industry: Principles, applications and challenges. Critical Reviews in Food Science and Nutrition. 2021;61(13):2107-24.
  49. Arora P, Sindhu A, Dilbaghi N, Chaudhury A. Biosensors as innovative tools for the detection of food borne pathogens. Biosensors and Bioelectronics. 2011;28(1):1-12.
  50. Rajeshkumar S, Lakshmi T, Tharani M, Sivaperumal P. Green synthesis of gold nanoparticles using pomegranate peel extract and its antioxidant and anticancer activity against liver cancer cell line. 2020.
Archives of Razi Institute
Volume 80, Issue 2
March and April 2025
Pages 385-394

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