1. Li S, Huang Y, Yu L, Ji X, Wu J. Impact of the
Cannabinoid System in Alzheimer's Disease. Current
Neuropharmacology. 2023;21(3):715-26.
2. Shen Z-X. Brain cholinesterases: III. Future
perspectives of AD research and clinical practice.
Medical hypotheses. 2004;63(2):298-307.
3. Castillo-Carranza DL, Lasagna-Reeves CA, Kayed R.
Tau aggregates as immunotherapeutic targets. Frontiers
in Bioscience-Scholar. 2013;5(2):426-38.
4. Gonzalez-Naranjo P, E Campillo N, Perez C, A Paez J.
Multitarget cannabinoids as novel strategy for
Alzheimer disease. Current Alzheimer Research.
2013;10(3):229-39.
5. Aso E, Palomer E, Juvés S, Maldonado R, Munoz FJ,
Ferrer I. CB 1 agonist ACEA protects neurons and
reduces the cognitive impairment of AβPP/PS1 mice.
Journal of Alzheimer's disease. 2012;30(2):439-59.
6. Raymundi AM, Stern CAJ. Role of hippocampal CB1
and CB2 receptors in fear memory consolidation,
extinction, and reconsolidation. Neurobiology and
Physiology of the Endocannabinoid System: Elsevier;
2023. p. 283-95.
7. Niloy N, Hediyal TA, Vichitra C, Sonali S,
Chidambaram SB, Gorantla VR, et al. Effect of
cannabis on memory consolidation, learning and
retrieval and its current legal status in India: A review.
Biomolecules. 2023;13(1):162.
8. Koppel J, Davies P. Targeting the endocannabinoid
system in Alzheimer's disease. Journal of Alzheimer's
Disease. 2008;15(3):495-504.
9. Murillo-Rodríguez E. The role of the CB1 receptor in
the regulation of sleep. Progress in NeuroPsychopharmacology and Biological Psychiatry.
2008;32(6):1420-7.
10. Bilkei-Gorzo A, Racz I, Valverde O, Otto M, Michel
K, Sarstre M, et al. Early age-related cognitive
impairment in mice lacking cannabinoid CB1 receptors.
Proceedings of the National Academy of Sciences.
2005;102(43):15670-5.
11. Davies SN, Pertwee RG, Riedel G. Functions of
cannabinoid receptors in the hippocampus.
Neuropharmacology. 2002;42(8):993-1007.
12. Da Silva GE, Takahashi RN. SR 141716A prevents
Δ9-tetrahydrocannabinol-induced spatial learning deficit
in a Morris-type water maze in mice. Progress in NeuroPsychopharmacology and Biological Psychiatry.
2002;26(2):321-5.
13. Takahashi RN, Pamplona FA, Fernandes MS. The
cannabinoid antagonist SR141716A facilitates memory
acquisition and consolidation in the mouse elevated Tmaze. Neuroscience letters. 2005;380(3):270-5.
14. Khodadadeh A, Hassanpour S, Akbari G. Effects of
hesperidin during pregnancy on antidepressant-like
behaviour in postpartum mice. Iranian Journal of
Veterinary Medicine. 2020;14(03):261-270.
15. Paxinos G, Watson C. The rat brain in stereotaxic
coordinates: hard cover edition: Elsevier; 2006.
16. Marchant NL, Reed BR, Sanossian N, Madison CM,
Kriger S, Dhada R, et al. The aging brain and cognition:
contribution of vascular injury and aβ to mild cognitive
dysfunction. JAMA neurology. 2013;70(4):488-95.
17. Elahinia A, Hassanpour S, Asghari A, Khaksar E.
Effects of α-pinene Administration During Pregnancy
on Depressive-like Behavior Following Delivery in
Mice. Iranian Journal of Veterinary Medicine.
2023;17(3).
18. Han J, Kesner P, Metna-Laurent M, Duan T, Xu L,
Georges F, et al. Acute cannabinoids impair working
memory through astroglial CB1 receptor modulation of
hippocampal LTD. Cell. 2012;148(5):1039-50.
19. Resae A, Yousefi MH, Naeimi S, Mahdavi A. Effects
of Occupational Formaldehyde Exposure on Passive
Avoidance Conditioning and Anxiety Levels in Wistar
Rats. Iranian Journal of Veterinary Medicine.
2023;17(1):65-74.
20. Albertazzi P. Noradrenergic and serotonergic
modulation to treat vasomotor symptoms. British
Menopause Society Journal. 2006;12(1):7-11.
21. Cassano T, Villani R, Pace L, Carbone A, Bukke VN,
Orkisz S, et al. From Cannabis sativa to cannabidiol:
Promising therapeutic candidate for the treatment of
neurodegenerative diseases. Frontiers in pharmacology.
2020;11:124.
22. Kobilo T, Hazvi S, Dudai Y. Role of cortical
cannabinoid CB1 receptor in conditioned taste aversion
memory. European Journal of Neuroscience.
2007;25(11):3417-21.
23. Nava F, Carta G, Battasi A, Gessa G. D2 dopamine
receptors enable Δ9‐tetrahydrocannabinol induced
memory impairment and reduction of hippocampal
extracellular acetylcholine concentration. British journal
of pharmacology. 2000;130(6):1201-10.
24. Lichtman AH, Dimen KR, Martin BR. Systemic or
intrahippocampal cannabinoid administration impairs
spatial memory in rats. Psychopharmacology.
1995;119:282-90.
25. Silva MH. Neurotoxic or Protective Cannabis
Components: Delta-9-Tetrahydrocannabinol (Δ9 THC)
and Cannabidiol (CBD). Journal of Exploratory
Research in Pharmacology. 2023;8(4):299-322.
942 Tavakoli Far et al / Archives of Razi Institute, Vol. 79, No. 5 (2024) 935-942
26. Rahmani B, Zendehdel M, Babapour V,
Sadeghinezhad J, Alirezaei M. Evaluation of Betaine
Neuroprotective Effects on 6-Hydroxy Dopamine
Induced Hemi Parkinsonism in Male Wistar Rats.
Iranian Journal of Veterinary Medicine. 2019;13(3):290-
302.
27. Ohno-Shosaku T, Maejima T, Kano M. Endogenous
cannabinoids mediate retrograde signals from
depolarized postsynaptic neurons to presynaptic
terminals. Neuron. 2001;29(3):729-38.
28. Sigel E, Baur R, Rácz I, Marazzi J, Smart TG,
Zimmer A, et al. The major central endocannabinoid
directly acts at GABAA receptors. Proceedings of the
National Academy of Sciences. 2011;108(44):18150-5.
29. Abate G, Uberti D, Tambaro S. Potential and limits of
cannabinoids in alzheimer’s disease therapy. Biology.
2021;10(6):542.