The Influence of Rumen-Protected Choline and α-tocopherol Supplementation on Early Lactating Dairy Cows Metabolism

Document Type : Original Articles

Authors

1 Department of Pharmacy, Al-Manara College for Medical Sciences, Maysan, Iraq

2 College of Technical Engineering, The Islamic University, Najaf, Iraq

3 Medical Laboratory Techniques Department, Al-Turath University College, Baghdad, Iraq

4 Education College, Al-Farahidi University, Baghdad, Iraq

5 Medical Laboratory Techniques Department, Dijlah University College, Iraq, Baghdad

6 Medical Laboratory Techniques Department, AL-Mustaqbal University College, Babylon, Iraq

7 Department of Pharmacy, Al-Nisour University College, Baghdad, Iraq

8 Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq

9 Altoosi University College, Najaf, Iraq

10 Al-Esraa University College, Baghdad, Iraq

11 Nursing Department, Hilla University College, Babylon, Iraq

Abstract

It is well documented that choline is known as one of the essential ingredients of phospholipids. Choline acts as a determinative element for appropriate cell membrane functions. On the other hand α-tocopherol (Vit E) is a fat-soluble vitamin. This vitamin acts as a strong antioxidant in the living body's defense system against oxidative stress. Lipid peroxidation in peripartum and early lactating cows is significantly increased while the level of serum Vit E is decreases dramatically. These concomitant physiological changes demonstrate a higher level of oxidative stress subsequently leads to serious health issues in dairy cows. Therefore, the present research was designed to investigate the following items in dairy cattle: 1) evaluation of the possible changes in serum protein fractions, and 2) comparing the oxidative status of orally RPC and vitamin E supplementation in dairy cows in early lactation period. In the current study 30 early lactating primiparous and multiparous Holstein cows (body condition score (BCS)=2.51 ± 0.10) were used beginning five weeks postpartum. All the animals were randomly divided in to three groups (n=10) (number of lactation=2.61). The animals were randomly assigned to receive one of the following treatments. Group 1 served as control group were not received any supplement. The second group was supplemented with 90 g/d of RPC (Reashre Choline, Balchem, USA). The third group was administrated 4400 IU/d vitamin E (Roche, Vitamins Ltd; Switzerland). In the current study, serum protein electrophoresis showed four main fractions as follows: albumin, α-globulin, β-globulin, and γ-globulin.  The recorded data showed that the percentages of albumin and γ-globulin fractions were higher in treated groups compared to the control group. In the animals supplementing with RPC and vitamin E the percentages of serum albumin increased to the value of 37. 70±1.63 and 38.21±1.28 respectively compare to the control group (34.69±1.21), which were significant (P<0.05).

Keywords

Main Subjects

References

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Archives of Razi Institute
Volume 77, Issue 3 - Serial Number 3
May and June 2022
Pages 1165-1171

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