Occurrence of multidrug-resistant Salmonella enterica serovar Enteritidis isolates from poultry in Iran

Document Type : Original Articles

Authors

Department of Microbiology, Razi vaccine and Serum Research Institute, Karaj, Iran

Abstract

Salmonella enterica is recognized as one of the major food-borne pathogens with more than 2,500 serotypes
worldwide. The present study addresses antimicrobial resistance of Salmonella enterica serovar Enteritidis
isolates in Iran. A collection of 151 Salmonella spp. isolates collected from poultry were serotyped to
identify Salmonella Enteritidis. Sixty-one Salmonella Enteritidis were subsequently tested against 30
antimicrobials. A high frequency of antimicrobial resistance was observed against nitrofurantoin (n=55,
90.2%) followed by nalidixic acid (n=41, 67.2%), and cephalexin (n=23, 37.7%). Multi-drug resistance
were observed in 35 (57.4%) out of 61 isolates. Twenty-six antimicrobial resistance patterns were observed
among the 61 Salmonella Enteritidis. All isolates were susceptible to ofloxacin, imipenem, enrofloxacin,
chloramphenicol, gentamicin, and 3rd and 4th generation cephalosporins. In conclusion, our results revealed
that implementing new policies toward overuse of antimicrobial drugs in Iranian poultry industry are of
great importance.

Keywords

Main Subjects

Article Title [French]

L’occurrence d’isolats multirésistants de Salmonella enterica serovar Enteritidis chez les volailles iraniennes

Abstract [French]

Salmonella enterica est reconnue comme l’un des principaux pathogènes d’origine alimentaire comptant plus de 2500 sérotypes à travers le monde. Cette étude a pour objectif d’évaluer la résistance antimicrobienne des isolats de Salmonella enterica serovar Enteritidis en Iran. Une collection de 151 espèces de Salmonella infectant les volailles ont fait l’objet d’un sérotypage afin d’identifier S. Enteritidis. Soixante et un isolats de S. Enteritidis ont été ensuite testés contre 30 agents antimicrobiens. Les plus fortes résistances antimicrobiennes ont été observées contre le nitrofurantoine (n=55, 90.2%), suivi par l’acide nalidixique (n=41, 67.2%), et la céphalexine (n=23, 37.7%). Trente cinq des 61 isolats testés étaient multirésistants. Cette étude a révélé 26 patterns différents de résistance antimicrobienne dans les 61 isolats analysés. Tous les isolats montraient une susceptibilité vis-à-vis de l’ofloxacine, l’imipenème, l’enrofloxacine, le chloramphénicol, la gentamicine, et la céphalosporine de troisième et quatrième générations. En conclusion, nos résultats reflètent la nécessité d’adopter de nouvelles politiques pour limiter l’emploi excessif de certains agents antimicrobiens dans l’industrie avicole iranienne.

Keywords [French]

  • Résistance antimicrobienne
  • Profile de résistance
  • multirésistance
  • Salmonella enterica

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Archives of Razi Institute
Volume 71, Issue 1
March and April 2016
Pages 43-49

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