An oil adjuvant vaccine (OAV) was prepared from a local strain of Pasteurella multocida. Strain 6:B was cultured and inactivated by formalin. Bacterial pellet was prepared by centrifugation and subsequently adjuvanted by Montannide oil ISA-70. A dose of prepared vaccine containing 3ml (2mg dry weight/ml) was injected into five calves by IM route. Animals were bled before and at 24, 90, 150, and 200 days post-vaccination. Collected sera were used in passive mouse protection test (PMPT). Active mouse protection test (AMPT) was carried out for OAV according to standard method. Results of PMPT showed 100% protection up to 150 days and 66-83% up to 200 days post-vaccination. In AMPT, 4 log of protection was gained. In this experiment the immunity induced by OAV adjuvanted by ISA-70 could protect the calves.
Sotoodehnia, A., Moazeni, G., Ataei, S., & Omidi, B. (2005). Study on Immunity of an Experimental Oil Adjuvant Haemorrhagic Septicaemia Vaccine in Cattle.. Archives of Razi Institute, 59(2), 95-101. doi: 10.22092/ari.2005.103817
MLA
A. Sotoodehnia; G. Moazeni; S. Ataei; B. Omidi. "Study on Immunity of an Experimental Oil Adjuvant Haemorrhagic Septicaemia Vaccine in Cattle.". Archives of Razi Institute, 59, 2, 2005, 95-101. doi: 10.22092/ari.2005.103817
HARVARD
Sotoodehnia, A., Moazeni, G., Ataei, S., Omidi, B. (2005). 'Study on Immunity of an Experimental Oil Adjuvant Haemorrhagic Septicaemia Vaccine in Cattle.', Archives of Razi Institute, 59(2), pp. 95-101. doi: 10.22092/ari.2005.103817
VANCOUVER
Sotoodehnia, A., Moazeni, G., Ataei, S., Omidi, B. Study on Immunity of an Experimental Oil Adjuvant Haemorrhagic Septicaemia Vaccine in Cattle.. Archives of Razi Institute, 2005; 59(2): 95-101. doi: 10.22092/ari.2005.103817