The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes

Document Type : Scientific Report


1 Department of Human Viral Vaccines, Razi Vaccine and Serum Research Institute, Karaj, Iran

2 Department of Clinical and Molecular Virology, KiaTech Virology Laboratory, karaj, Iran


Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection including the decline in the general incidence of HSV-1 infection in childhood and the increased rate of genital herpes, caused by HSV-1. Moreover, changes in the epidemiology of ocular herpes, i.e., the reduced rate of primary ocular herpes in children and increased incidence of ocular HSV infection in adults, were discussed. 


Main Subjects

Article Title [French]

L’épidémiologie changeante de l’infection au virus de l’herpès simplex de type 1 (HSV-1) : les effets associés à l’incidence de l’herpès oculaire

Abstract [French]

L’herpès simplex de type 1 (HSV-1) est un virus distribué mondialement, touchant toutes les tranches de la population. Bien que l’HSV de type 2 (HSV-2) est reconnu comme la cause principale d’herpès génital, un nombre croissant de ces infections sont causés par l’ HSV-1. L’objectif de cette étude est d’examiner l’épidémiologie changeante des infections causées par l’ HSV-1, montrant une diminution de l’incidence générale chez l’enfant alors que le taux d’herpès génital causé par HSV-1 est en augmentation. De plus, les changements observés dans l’épidémiologie de l’herpès oculaire, en l’occurrence la réduction de l’herpès oculaire primaire infantile et l’incidence croissante des infections oculaires causées par l’HSV chez l’adulte sont également abordés.

Keywords [French]

  • L’herpès simplex de type 1 (HSV-1)
  • Herpès oculaire
  • Herpès génital
  • Epidémiologie
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