Antibiotic resistance / susceptibility of 30 isolates of Bacillus anthracis isolated in Iran between 2007 and 2008

Banihashemi, R.; Razzaz, H.; Tadayon, K.; Bakhshi, B.; Moazeni Jula, G.

doi:10.22092/ari.2016.103874

Antibiotic resistance / susceptibility of 30 isolates of Bacillus anthracis isolated in Iran between 2007 and 2008

Authors

10.22092/ari.2016.103874

Abstract

Thirty isolates of Bacillus anthracis recovered from animal carcasses, soil and human in different localities
in Iran between 2007 and 2008. They were tested by standard disc diffusion susceptibility method for their
resistant/ susceptibility to different kinds of antibiotics. According to American National Committee of
Clinical Laboratory Standards (NCCLS) guidelines all isolates were sensitive to levofloxacin (100%),
cefixime (100%). Other isolates showed different kinds of sensitivity to: doxycycline (96.7%), cephalothin
(95.6%), ampicillin (95.6%), nitrofurantoin (95.6%), tetracycline (94.4%), ofloxacin (89.9%), gentamycin
(77.8%), nalidixic acid (72.2%), kanamycin (75.6%), erythromycin (71.1%), piperacillin (78.9%),
tobramycin(64.4%), choramphenicol (59.9%), cefotaxime (33.3%), ciprofloxacin (1.1%), cefuroxime
(33.3%), azithromycin (44.4%), streptomycin (55.6%), ticacillin (35.6%), rifampicin (34.4%), clindamycin
(74.4%), ceftriaxon (26.7%), methicillin (55.6%), trimethoprim (8.9%), cloxacillin (31.1%) and penicillin
(74.4%). One of the isolates was complete resistance to penicillin.Therefore, preventive and therapeutic
strategies involving the use of antibiotics should take the possibility of resistance and/or susceptibility of the
isolates into account and not decided without antibiotic sensitivity testing.

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