TY - JOUR ID - 106451 TI - The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes JO - Archives of Razi Institute JA - ARI LA - en SN - 0365-3439 AU - Abedi Kiasari, B. AU - Zare Tooranposhti, Z. AD - Department of Human Viral Vaccines, Razi Vaccine and Serum Research Institute, Karaj, Iran AD - Department of Clinical and Molecular Virology, KiaTech Virology Laboratory, karaj, Iran Y1 - 2016 PY - 2016 VL - 71 IS - 2 SP - 125 EP - 134 KW - Herpes simplex virus type 1 (HSV-1) KW - Ocular herpes KW - Genital herpes KW - Epidemiology DO - 10.22034/ari.2016.106451 N2 - Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection including the decline in the general incidence of HSV-1 infection in childhood and the increased rate of genital herpes, caused by HSV-1. Moreover, changes in the epidemiology of ocular herpes, i.e., the reduced rate of primary ocular herpes in children and increased incidence of ocular HSV infection in adults, were discussed.  UR - https://archrazi.areeo.ac.ir/article_106451.html L1 - https://archrazi.areeo.ac.ir/article_106451_d292880921994bf92ebe26dd1f28c252.pdf ER -