%0 Journal Article %T The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes %J Archives of Razi Institute %I Razi Vaccine & Serum Research Institute %Z 0365-3439 %A Abedi Kiasari, B. %A Zare Tooranposhti, Z. %D 2016 %\ 06/01/2016 %V 71 %N 2 %P 125-134 %! The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes %K Herpes simplex virus type 1 (HSV-1) %K Ocular herpes %K Genital herpes %K Epidemiology %R 10.22034/ari.2016.106451 %X Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection including the decline in the general incidence of HSV-1 infection in childhood and the increased rate of genital herpes, caused by HSV-1. Moreover, changes in the epidemiology of ocular herpes, i.e., the reduced rate of primary ocular herpes in children and increased incidence of ocular HSV infection in adults, were discussed.  %U https://archrazi.areeo.ac.ir/article_106451_d292880921994bf92ebe26dd1f28c252.pdf