@article { author = {Abedi Kiasari, B. and Zare Tooranposhti, Z.}, title = {The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes}, journal = {Archives of Razi Institute}, volume = {71}, number = {2}, pages = {125-134}, year = {2016}, publisher = {Razi Vaccine & Serum Research Institute}, issn = {0365-3439}, eissn = {2008-9872}, doi = {10.22034/ari.2016.106451}, abstract = {Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections. Although HSV type 2 (HSV-2) is known as the most common cause of genital herpes, an increasing number of cases with genital herpes are caused by HSV-1. The present study aimed to discuss the changes in the epidemiology of HSV-1 infection including the decline in the general incidence of HSV-1 infection in childhood and the increased rate of genital herpes, caused by HSV-1. Moreover, changes in the epidemiology of ocular herpes, i.e., the reduced rate of primary ocular herpes in children and increased incidence of ocular HSV infection in adults, were discussed. }, keywords = {Herpes simplex virus type 1 (HSV-1),Ocular herpes,Genital herpes,Epidemiology}, url = {https://archrazi.areeo.ac.ir/article_106451.html}, eprint = {https://archrazi.areeo.ac.ir/article_106451_d292880921994bf92ebe26dd1f28c252.pdf} }